There’s a special kind of magic to traveling Route 66, one that is highlighted so often in songs, movies, and famous road trip travelogues. Hitting the pavement along this coveted route provides a sense of nostalgia, of stepping into a slower, simpler time where neon signs light the way and friendly small towns offer hospitality that feels lost in today’s fast-paced world.

Known as the “Mother Road,” Route 66 once connected Chicago to Santa Monica, and though much of the highway has been decommissioned, the spirit of the journey is alive and well in the small towns that dot its path. These communities offer a look into the past, rich with quirky roadside attractions, classic diners, and genuine Americana.

With the upcoming centennial celebrations of Route 66 next year, we wanted to highlight some of the best, quirkiest towns along the route to take you back to the good old days. Here they are in no particular order.

1. Seligman, Arizona 

Often regarded as the birthplace of the Route 66 revival, Seligman is a colorful town that embraces its role in keeping the spirit of the highway alive. With vintage cars lining the streets, murals on nearly every building, and the legendary Delgadillo’s Snow Cap Drive-In serving up burgers and laughs, Seligman feels like a living museum, and was a key inspiration for the fictional town of Radiator Springs in “Cars.”

If you’re looking for a unique place to stay in Seligman, Arizona, check out this Route 66 Railroad House Airbnb.

2. Shamrock, Texas

Shamrock’s crown jewel is the U-Drop Inn, an Art Deco gas station that now serves as a visitor center and inspiration for the Cars movie. The town celebrates Irish heritage with a St. Patrick’s Day festival and offers plenty of vintage Route 66 vibes. This small town in Texas is a must-visit stop if you love vintage automobiles, history, and a solid dose of nostalgia.

Spend the night at the Route 66 Inn in Shamrock, Texas!

3. El Reno, Oklahoma

A gem in central Oklahoma, El Reno is famous for the fried onion burger, a Route 66 classic. Each May, the town celebrates Burger Day with a giant skillet that cooks up thousands of patties. El Reno also features vintage architecture, a historic downtown, and the Canadian County Historical Museum.

4. Pontiac, Illinois

Pontiac, Illinois, is the perfect place to pause on your Route 66 journey, offering a big dose of quintessential small town energy. With a walkable downtown full of murals, vintage signage, and museums—including the Route 66 Association Hall of Fame—it’s a hub of nostalgia. Be sure to snap a photo with the oversized Route 66 street shield and enjoy a stroll along the Vermilion River.

5. Galena, Kansas

With less than five miles of Route 66 running through it, Galena packs in a surprising amount of character. Visit Cars on the Route, a restored gas station that inspired the movie “Cars,” and wander the revitalized Main Street full of mining history and friendly faces.

Galena has an incredible Treehouse Airbnb, perfect for an overnight on your journey.

6. Sapulpa, Oklahoma

Sapulpa is one of Oklahoma’s best-kept Route 66 secrets. With beautifully restored buildings, antique shops, and Route 66-themed murals, the town celebrates both its oil boom past and its Mother Road legacy. Check out the Sapulpa Historical Museum and enjoy a slice of small-town charm.

7. Cuba, Missouri 

Nicknamed “Mural City,” Cuba, Missouri, boasts over a dozen large-scale public artworks that tell the story of the region’s people and history. The historic Wagon Wheel Motel and rock buildings around town add architectural character to this artistic stop along Route 66.

8. Tucumcari, New Mexico

If you’re a fan of neon, Tucumcari is a must-stop. This New Mexico gem is famous for its classic motels—like the Blue Swallow, with its glowing blue signage and vintage garages. The town’s many murals and Route 66 Museum provide a deeper dive into the culture and history of mid-century road travel.

It doesn’t get much better than this castle-style Airbnb in Tucumcari to stay the night.

9. Amarillo, Texas

While larger than most towns on this list, Amarillo captures the Route 66 spirit with a mix of classic roadside kitsch and Texas flavor. Don’t miss Cadillac Ranch, a field of half-buried, spray-painted cars. Historic Sixth Street is lined with retro shops, antique stores, and vintage eateries.

10. Santa Monica, California

While Santa Monica isn’t a small town, it’s the symbolic end of the road—and every Route 66 journey deserves a grand finale. Walk out to the end of the Santa Monica Pier and take a photo with the official “End of the Trail” sign. After your long journey west, dip your toes in the Pacific and reflect on the incredible cross-country adventure you’ve just completed.

Ending the journey and waking up to the waves in Santa Monica? Sign me up!

Traveling Route 66 isn’t just about the road, it’s about the people, the stories, and the small towns that keep its legacy alive. Each of these places adds a different layer to the Route 66 experience, from roadside diners and restored motels to neon lights and desert vistas.

Memphis is the destination for Elvis Presley fans, with Graceland alone attracting about 600,000 visitors a year.